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Methylation been found on a variety of lysine residues in varied histones: K4 (using the one-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, legal practice K20 in histone H4, K59 in the globular domain of histone H4 2 and K26 of histone H1B 3 A number of proteins liable for the methylation of specific residues have been characterised, and all however one of these accommodates a SET area